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The Genetic Biolab - Advanced is a stage which first appeared in Dead or Alive 4 as Biolab Core. The stage is located in the main headquarters of DOATEC and where the game's final boss Alpha-152 is located.
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In Dead or Alive 4, the biolab is used as the final boss stage when the player fights Alpha-152. The clone is fought in the following characters' stories: Kasumi, Ryu Hayabusa, Brad Wong, Zack, Jann Lee, and La Mariposa.